• Ostomy Care
  • Peristomal Skin Health
  • Skin Health Evidence
  • ADVOCATE Study

CeraPlus™ Skin Barrier with Remois Technology* Minimises Potential Impact of Peristomal Skin Complications from Day One5

The ADVOCATE study brings clinical evidence to help support decision making.

1 in 5 ostomy patients seek treatment for PSCs4

Peristomal skin complications (PSCs) lower health-related quality of life and raise cost of care.1-3 Yet, often they are considered just part of life with a stoma.

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ADVOCATE Study design

  • 153 participants
  • Double-blinded study
  • 25 sites in a multicentre, multinational trial
  • Adaptive design planned for two interim analyses

Results

More CeraPlus™ skin barrier users resolved skin complications within a four-week period5

53% vs 29%
 

15% fewer PSCs in the CeraPlus™ skin barrier group5

15% fewer
 

More CeraPlus™ skin barrier users "very satisfied" with overall performance5

75% vs 55%
 

CeraPlus™ Skin Barrier

Helps maintain healthy skin from day one.

Ceramide-infused formulation helps protect against damage, dryness, and itching.

The CeraPlus™ skin barrier comes in a range of fit options including one-piece, two-piece, flat, firm convex, soft convex, tape border, and tapeless.

 

Request Free Sample

 

* compared to non-ceramide skin barriers from Hollister Ostomy Care

 

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CeraPlus™ skin barrier proved more effective than SenSura Mio skin barrier6 **

See the Proof

Fit + Formulation is the inspiration behind CeraPlus™ skin barrier

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*Remois is a technology of Alcare, Co., Ltd.
**SenSura Mio is a trademark of Coloplast A/S and its affiliates
As compared to Hollister Ostomy Care non-ceramide skin barriers
40.5% had PSCs in treament group vs 55.4% in control, p=0.069. (Not statistically significant)

 

References:

  1. Persson E, Gustavsson B, Hellstro A, Lappas G, Hulten L. Ostomy patients' perceptions of quality of care. J Adv Nurs. 2005;49(1):51-58.
  2. Gray M, Colwell JC, Doughty D, et al. Peristomal moisture associated skin damage in adults with fecal ostomies: a comprehensive review and consensus. J Wound Ostomy Continence Nurs. 2013;40(4):389-399.
  3. Coons SJ, Chongpison Y, Wendel CS, Grant M, Krouse RS. Overall quality of life and difficulty paying for ostomy supplies in the Veterans Affairs ostomy-related quality of life study. Med Care. 2007;45(9):891-895.
  4. Nybaek H, Band KD, Norgaar LT, Karlsmark T, Jemec GB. Skin problems in ostomy patients: a case control study of risk factors. Acta Derm Venereol. 2009;89(1):64-67.
  5. Colwell J, Pittman J, Raizman R, Salvadalena G. A Randomized Controlled Trial Determining Variances in Ostomy Skin Conditions (ADVOCATE). J Wound Ostomy Continence Nurs. 2018;45(1):37-42.
  6. Grove G. Houser T, Sibbald G. Salvadalena G. Measuring epidermal effects of ostomy skin barriers. Skin Res Technol. 2019;25:179-186. https://doi.org/10.1111/srt.12630

 

© 2024 Hollister Incorporated
© 2024 Hollister Incorporated

Prior to use, be sure to read the Instructions for Use for information regarding Intended Use, Contraindications, Warnings, Precautions, and Instructions.

The information provided herein is not medical advice and is not intended to substitute for the advice of your personal physician or other healthcare provider. This information should not be used to seek help in a medical emergency. If you experience a medical emergency, seek medical treatment in person immediately.

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